audio 64kbps mono In summary: * Bitrates of 128kbps are for library use for music, and should not be used for Internet audio. * Instead, MP3 at 32kbps is suitable for speech and general podcasting. you should use two-pass encoding. It is more time consuming to encode, because the video to be encoded is analysed in a first pass. However, two-pass encoding results in better video for the same bitrate and filesize. "don't use variable bit rate" for streaming For MP4 formats, make sure that you retain "forced key frames": At that screen size, for a talking head video and speech only audio you need about 3-500Kbps video and 48-64Kbps audio. But if your content is fast moving (sports for example), you have to pump 2-2.5Mbps video and 128Kbps audio for high quality. Obviously, if you go over 1.5Mbps total, you exclude lots of viewers, everyone with slower internet (basic DSL).